H-151, CAS 941987-60-6

Product Description: H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease[1].

Applications: COVID-19-immunoregulation

Formula: C17H17N3O

References: [1]Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.

CAS Number: 941987-60-6

Molecular Weight: 279.34

Compound Purity: 99.86

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: STING

• SKU: MEXHY-112693-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112693-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK