HCH6-1, CAS 1435265-06-7

Product Description: HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1].

Applications: COVID-19-immunoregulation

Formula: C28H27N3O4

References: [1]Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269

CAS Number: 1435265-06-7

Molecular Weight: 469.53

Compound Purity: 99.14

Research Area: Inflammation/Immunology

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Formyl Peptide Receptor (FPR)

• SKU: MEXHY-101283-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101283-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK