Target: HCN4
Conjugate: HRP
Product Type: Monoclonal
Clone Number: N114/10 (Formerly sold as S114-10)
Immunogen: Fusion protein amino acids 1019-1198 (c-terminus) of rat HCN4
Swiss-Prot: Q9JKA7
Purification: Protein G Purified
Storage Buffer: 73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O
Concentration: 1 mg/ml
Specificity: Detects ~130kDa. No cross-reactivity against other HCNs.
Cellular Localization: Membrane
Scientific Background: Hyperpolarization-activated cation channels of the HCN gene family contribute to spontaneous rhythmic activity in both the heart and brain (1).
References: 1. Zong X., et al. (2005) J Biol Chem. 280(40): 34224-34245
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.