Clone Name: HL3420
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 119
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Uniprot ID: P56524
Antigen Species: Human
Immunogen: Recombinant fragment of human HDAC4.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: histone deacetylase 4
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