HDAC6 Inhibitor, CAS 1259296-46-2

Shelf life (days): 730.0

Formulation: A solution in acetonitrile

Formal Name: 1,2,3,4-tetrahydro-N-hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-6-isoquinolinecarboxamide

Purity: ≥95%

Formula Markup: C16H17N3O3

Formula Weight: 299.3

CAS Number: 1259296-46-2

Notes: HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates.{26999} In this way, it impacts development, proliferation, invasion, and tumorigenesis.{26999} HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks other HDAC enzymes.{24174} It is cell permeable, inhibiting the acetylation of tubulin in cells with an IC50 value of 210 nM.{24174}

• SKU: CAY15200-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15200-5
• Package Unit: 5 mg
• Quantity Unit: STK