HDAC8-IN-1, CAS 1417997-93-3

Product Description: HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM.

Applications: Cancer-programmed cell death

Formula: C22H19NO3

References: [1]Huang WJ, et al. Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitors. ChemMedChem. 2012 Oct;7(10):1815-24./[2]Cui J, et al., IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation. Cell Death Dis. 2021 May 18;12(6):501.

CAS Number: 1417997-93-3

Molecular Weight: 345.39

Compound Purity: 99.82

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HDAC

• SKU: MEXHY-111342-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111342-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK