HIF-2α-IN-3, CAS 313964-19-1

Product Description: HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α (HIF-2α), exhibits an IC50 of 0.4 μM and a KD of 1.1 μM. Anticancer agent[1].

Applications: Cancer-programmed cell death

Formula: C12H6ClN5O5

References: [1]Rogers JL, et al. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. J Med Chem. 2013 Feb 28;56(4):1739-47.

CAS Number: 313964-19-1

Molecular Weight: 335.66

Compound Purity: 99.89

Research Area: Cancer

Solubility: DMSO : 12.5 mg/mL (ultrasonic)

Target: HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-18370-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18370-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK