Description: Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels.
CAS Number: 7729-23-9
Formula: C22H28N2O3
Molecular Weight: 368,47
References: Selective anticancer activity of hirsutine against HER2-positive breast cancer cells by inducing DNA damage.Oncol Rep. 2015 Apr;33(4):2072-6.