Product Description: HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with Kds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC50 of 200 nM. HS38 can be used for the research of smooth muscle related disorders[1].
Formula: C14H12ClN5O2S
References: [1]David A Carlson, et al. Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor. ACS Chem Biol. 2013 Dec 20; 8(12): 2715–2723.
CAS Number: 1030203-81-6
Molecular Weight: 349.80
Compound Purity: 99.0
Research Area: Cardiovascular Disease
Solubility: DMSO : 7.14 mg/mL (ultrasonic)
Target: DAPK