Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]
Description: Recombinant Human CLEC5A Protein with N-terminal human Fc tag
Molecular Weight: The protein has a predicted molecular mass of 44.5 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CLEC5A is approximately 55-70 kDa due to glycosylation.
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: N-Human Fc Tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target: CLEC5A
Uniprot ID: Q9NY25
Usage: Research use only
Molecular Characterization: hFc(Glu99-Ala330) CLEC5A(Pro28-Lys188)
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
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