Human EPCAM Protein, His Tag

Background: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Description: Recombinant human EPCAM protein with C-terminal 6×His tag

Molecular Weight: The protein has a predicted molecular mass of 28.2 kDa after removal of the signal peptide.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Tag: C-6×His Tag

Expression Host: HEK293

Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Target: EPCAM

Uniprot ID: P16422

Usage: Research use only

Molecular Characterization: EPCAM(Gln24-Lys265) 6×His tag

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

• SKU: DMAPME100068-50
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: PME100068-50
• Package Unit: 50 µg
• Quantity Unit: STK
• Conjugate: Unconjugated