Human IgG1-Fc Protein

Background: IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include Leukemia;Chronic Lymphocytic and Heavy Chain Deposition Disease. Among its related pathways are Interleukin-4 and 13 signaling and IL4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include antigen binding. An important paralog of this gene is IGHG3.

Description: Recombinant Human IgG1-Fc Protein

Molecular Weight: The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide.The apparent molecular mass of IgG1-Fc is approximately 30-40 kDa due to glycosylation.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expression Host: HEK293

Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Target: IgG1-Fc

Uniprot ID: P01857

Usage: Research use only

Molecular Characterization: hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

• SKU: DMAPME100499-50
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: PME100499-50
• Package Unit: 50 µg
• Quantity Unit: STK
• Conjugate: Unconjugated