Background: This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Description: Human TA2R-Strep full length protein-synthetic nanodisc
Molecular Weight: The human full length TA2R-Strep protein has a MW of 37.4 kDa
Protein Families: GPCR,Transmembrane,Druggable Genome,
Protein Pathways: GPCRDB Class A Rhodopsin-like,Small ligand GPCRs,Angiogenesis,Metabolic and Obesity,
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: C-Flag&Strep Tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Target: TA2R
Uniprot ID: P21731
Usage: Research use only
English
Deutsch
