Hydroxy-α-sanshool, CAS 83883-10-7

Product Description: Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 μM, respectively. Hydroxy-α-sanshool can be used for pain research[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C16H25NO2

References: [1]Koo JY, et al. Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol. 2009 Aug;157(8):1398-409./[2]Koo JY, et al. Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. Eur J Neurosci. 2007 Sep;26(5):1139-47.

CAS Number: 83883-10-7

Molecular Weight: 263.38

Compound Purity: 99.57

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Endogenous Metabolite;TRP Channel

• SKU: MEXHY-N6825-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N6825-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK