Product Description: IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS)), autism spectrum disorders (ASD) and Down syndrome (DoS)[1].
Formula: C17H25F3N2O4S
References: [1]Annalisa Savardi, et al. Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with Defective NKCC1/KCC2 expression-ratio (P2-12.003). April 25, 2023 issue 100 (17_supplement_2).
CAS Number: 2497525-96-7
Molecular Weight: 410.45
Research Area: Neurological Disease
Target: NKCC