ICCB280, CAS 2041072-41-5

Product Description: ICCB280 is a potent inducer of C/EBPα. ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPα and affecting its downstream targets (such as C/EBPε, G-CSFR and c-Myc)[1][2].

Applications: Cancer-programmed cell death

Formula: C23H18N2O4

References: [1]Radomska HS, et, al. A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation. J Biomol Screen. 2015 Oct;20(9):1150-9./[2]Sridhar R, et, al. Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα. Molecules. 2018 Aug 3;23(8):1938.

CAS Number: 2041072-41-5

Molecular Weight: 386.40

Compound Purity: 99.43

Research Area: Cancer

Solubility: DMSO : 83.33 mg/mL (ultrasonic)

Target: Apoptosis

• SKU: MEXHY-134333-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134333-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK