ICI 162846, CAS 84545-30-2

Product Description: ICI 162846 is an orally active antagonist of H2 receptor. ICI 162846 inhibits acid production accompanied by an increase in the secretion of histamine in chronic duodenal ulcer (CDU) models. ICI 162846 is effective in preventing CDU[1][2].

Applications: COVID-19-immunoregulation

Formula: C11H17F3N6O

References: [1]Wilson JA, et al. Inhibition of human gastric secretion by ICI 162,846--a new histamine H2-receptor antagonist. Br J Clin Pharmacol. 1986 Jun;21(6):685-9./[2]Gompertz RH, et al. Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents Actions. 1991 May;33(1-2):161-3.

CAS Number: 84545-30-2

Molecular Weight: 306.29

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Histamine Receptor

• SKU: MEXHY-101234-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101234-10
• Package Unit: 10 mg
• Quantity Unit: STK