ID-8, CAS 147591-46-6

Product Description: ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK). ID-8 sustains embryonic stem cell (ESC) self-renewal and pluripotency. ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs[1][2].

Applications: Cancer-Kinase/protease

Formula: C16H14N2O4

References: [1]Hasegawa, K., et al., Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem Cells Transl Med, 2012. 1(1): p. 18-28./[2]Miyabayashi, T., et al., Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Biosci Biotechnol Biochem, 2008. 72(5): p. 1242-8.

CAS Number: 147591-46-6

Molecular Weight: 298.29

Compound Purity: 99.92

Research Area: Cancer

Solubility: DMSO : ≥ 47 mg/mL

Target: DYRK

• SKU: MEXHY-15838-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15838-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK