Product Description: IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging[1].
Applications: Neuroscience-Neuromodulation
Formula: C8H9ClN2O2S
References: [1]Buccafusco JJ, et al. The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology. 2004 Jan;46(1):10-22. doi: 10.1016/j.neuropharm.2003.07.002./[2]Yamada KA, et al. The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury. Ann Neurol. 1998 May;43(5):664-9.
CAS Number: 22503-72-6
Molecular Weight: 232.692
Compound Purity: 99.66
Research Area: Neurological Disease
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: iGluR
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