IL-4 Inhibitor, CAS 1332184-63-0

Shelf life (days): 730.0

Formulation: A crystalline solid

Formal Name: 2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)-3-pyridinecarbonitrile

Purity: ≥98%

Formula Markup: C18H12FN3O2

Formula Weight: 321.305303

CAS Number: 1332184-63-0

Notes: IL-4 inhibitor is an inhibitor of IL-4.{54527} It binds to IL-4 with a Kd value of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 μM). It is selective for IL-4 over IL-13 (EC50 = 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.

• SKU: CAY32548-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 32548-10
• Package Unit: 10 mg
• Quantity Unit: STK