Clone Name: 31H23
Application Note: WB: 1:100 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 25
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
Uniprot ID: P29459
Antigen Species: Human
Immunogen: Recombinant Human IL-12 p70
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: interleukin 12A
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