IL7 antibody (12T6)

Clone Name: 12T6

Application Note: WB: 1:500 - 1:2000. IHC-P: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 20

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]

Uniprot ID: P13232

Antigen Species: Human

Immunogen: Human recombinant IL-7

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: interleukin 7

• SKU: GTX52864-50
• Manufacturer: GeneTex
• Manufacturer SKU: GTX52864-50
• Package Unit: 50 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin), Western Blotting, Neutralization, Inhibition Assay
• Isotype: IgG1
• Human Gene ID: 3574
• Host: Mouse
• Conjugate: Unconjugated