IMT1, CAS 2304621-31-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-propanamide

Purity: ≥98%

Formula Markup: C21H21NO4

Formula Weight: 351.402

CAS Number: 2304621-31-4

Notes: A POLRMT inhibitor; selectively inhibits POLRMT transcription over six other RNA polymerases at 1 µM; decreases mitochondrial mRNA transcripts and DNA levels in HeLa cells at 0.05-10 µM; reduces oxygen flux in HeLa cells at 0.5, 1, or 5 µM; decreases the levels of dATP, dCTP, and dTTP and the levels of citric acid cycle intermediates in A2780 cells at 0.1 µM; decreases tumor volume in an A2780 mouse xenograft model at 100 mg/kg per day

• SKU: CAY43029-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43029-5
• Package Unit: 5 mg
• Quantity Unit: STK