Indophagolin, CAS 1207660-00-1

Description: Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.

CAS Number: 1207660-00-1

Formula: C19H15BrClF3N2O3S

Molecular Weight: 523,75

References: Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.

• SKU: TGMT8946-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T8946-5mg
• Package Unit: 5 mg
• Quantity Unit: STK