INF4E, CAS 88039-46-7

Product Description: INF4E is a potent NLRP3 inflammasome inhibitor. INF4E inhibits caspase-1 and NLRP3 ATPase activities. INF4E shows protection against the IR-induced myocardial injury and dysfunction[1][2].

Applications: COVID-19-immunoregulation

Formula: C12H13ClO3

References: [1]Shi Y, et al. NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages. Int Immunopharmacol. 2021 Mar;92:107358./[2]Mezzaroma E,et al. NLRP3 Inflammasome Inhibitors in Cardiovascular Diseases. Molecules. 2021 Feb 12;26(4):976./[3]occo M, et al. Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis. J Med Chem. 2014 Dec 26;57(24):10366-82.

CAS Number: 88039-46-7

Molecular Weight: 240.68

Compound Purity: 99.38

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-121988-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121988-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK