INH14, CAS 200134-22-1

Product Description: INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity[1].

Applications: Neuroscience-Neuromodulation

Formula: C15H16N2O

References: [1]Drexel M, et al. INH14, a Small-Molecule Urea Derivative, Inhibits the IKKα/β-Dependent TLR Inflammatory Response. Chembiochem. 2019 Mar 1;20(5):710-717.

CAS Number: 200134-22-1

Molecular Weight: 240.30

Compound Purity: 98.0

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : ≥ 125 mg/mL

Target: IKK

• SKU: MEXHY-114454-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-114454-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK