INK4C-IN-2, CAS 6314-70-1

Product Description: INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model[1].

Formula: C13H17NO4S

References: [1]Xie XQ, et al., Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115.

CAS Number: 6314-70-1

Molecular Weight: 283.34

Compound Purity: 98.10

Research Area: Cancer

Target: CDK

• SKU: MEXHY-108420-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108420-50
• Package Unit: 50 mg
• Quantity Unit: STK