Integrin alpha 4 antibody (2L30)

Clone Name: 2L30

Application Note: IHC-Fr: 1:20 - 1:100. FCM: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Uniprot ID: P13612

Antigen Species: Human

Immunogen: Human recombinant Integrin α4

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: integrin subunit alpha 4

• SKU: GTX52871-50
• Manufacturer: GeneTex
• Manufacturer SKU: GTX52871-50
• Package Unit: 50 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Flow Cytometry
• Isotype: IgG1
• Human Gene ID: 3676
• Host: Mouse
• Conjugate: Unconjugated