Integrin alpha 6 antibody (2F37)

Clone Name: 2F37

Application Note: IHC-Fr: 1:50 - 1:200. FACS: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 127

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Uniprot ID: P23229

Antigen Species: Human

Immunogen: Human recombinant Integrin α6

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: integrin subunit alpha 6

• SKU: GTX52874-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX52874-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Flow Cytometry
• Isotype: IgG2
• Human Gene ID: 3655
• Host: Mouse
• Conjugate: Unconjugated