Shelf life (days): 730.0
Formulation: A solution in ethanol
Formal Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
Purity: ≥95%
Formula Markup: C41H72O9
Formula Weight: 709.0
CAS Number: 56092-81-0
Notes: Ionomycin is a calcium ionophore originally isolated from S. conglobatus.{19988} It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils.{58291} Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.{58292,58293}
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