IRAK4 (N Terminus) blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89550.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Region Sequence: NKPITPSTYVRC

Full Name: interleukin 1 receptor associated kinase 4

• SKU: GTX89550-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89550-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 51135