Irosustat, CAS 288628-05-7

Product Description: Irosustat is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.

Applications: Cancer-programmed cell death

Formula: C14H15NO5S

References: [1]Purohit A, et al. In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE. Cancer Res. 2000 Jul 1;60(13):3394-6./[2]Raobaikady B, et al. Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):351-8.

CAS Number: 288628-05-7

Molecular Weight: 309.34

Compound Purity: 99.72

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Steroid Sulfatase

• SKU: MEXHY-14586-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14586-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK