Product Description: Isbogrel (CV-4151) is a potent selective inhibitor of thromboxane A2 synthase. Isbogrel has oral activity and inhibits blood TXA2 generation with an ID50 value of 0.04 mg/kg[1].
Applications: Cancer-programmed cell death
Formula: C18H19NO2
References: [1]Z Terashita, et al. Effects of thromboxane A2 synthase inhibitors (CV-4151 and ozagrel), aspirin, and ticlopidine on the thrombosis caused by endothelial cell injury. Thromb Res. 1995, 77, 5.
CAS Number: 89667-40-3
Molecular Weight: 281.35
Research Area: Cancer; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Prostaglandin Receptor