Product Description: Isoorientin is a potent inhibitor of COX-2 with an IC50 value of 39 μM.
Applications: Cancer-programmed cell death
Formula: C21H20O11
References: [1]Sumalatha M, et al. Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa. Nat Prod Commun. 2015 Oct;10(10):1703-4./[2]Ye T, et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther. 2016 Dec 12;9:7481-7492./[3]Anilkumar K, et al. Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa. Oxid Med Cell Longev. 2017;2017:5498054.
CAS Number: 4261-42-1
Molecular Weight: 448.38
Compound Purity: 99.26
Research Area: Cancer; Inflammation/Immunology
Solubility: DMSO : ≥ 100 mg/mL
Target: COX
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