Isradipine, CAS 75695-93-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 3-methyl 5-(1-methylethyl) ester

Purity: ≥98%

Formula Markup: C19H21N3O5

Formula Weight: 371.4

CAS Number: 75695-93-1

Notes: Isradipine is a selective L-type calcium channel blocker with long-acting antihypertensive activity.{28540} It demonstrates an EC50 value of 1.4 nM for relaxation of depolarization-induced contractions of rabbit aorta and an EC25 value of 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria.{28540} By suppressing calcium influx into the cytoplasm and Cav1.2 expression, isradipine has been shown to attenuate β-amyloid oligomer toxicity in an in vitro model of Alzheimer’s disease.{28541}

• SKU: CAY17536-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17536-25
• Package Unit: 25 mg
• Quantity Unit: STK