Ivosidenib, CAS 1448347-49-6

Product Description: Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity[1].

Applications: Cancer-programmed cell death

Formula: C28H22ClF3N6O3

References: [1]Popovici-Muller J, et al. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1Mutant Cancers. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305.

CAS Number: 1448347-49-6

Molecular Weight: 582.96

Compound Purity: 99.89

Research Area: Cancer; Metabolic Disease

Solubility: DMSO : ≥ 39 mg/mL

Target: Isocitrate Dehydrogenase (IDH)

• SKU: MEXHY-18767-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18767-25
• Package Unit: 25 mg
• Quantity Unit: STK