Product Description: Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
Applications: Cancer-Kinase/protease
Formula: C14H19BCl2N2O4
References: [1]Friedman JR, et al. Anticancer Activity of Natural and Synthetic Capsaicin Analogs. J Pharmacol Exp Ther. 2018 Mar;364(3):462-473.
CAS Number: 1072833-77-2
Molecular Weight: 361.03
Compound Purity: 99.85
Research Area: Cancer
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: Autophagy;Proteasome