JAK1/2-IN-1, CAS 3023876-01-6

Product Description: JAK1/2-IN-1 is a potent JAK1 and JAK2 inhibitor with IC50 values of 0.4 nM and 8.1 nM, respectively. JAK1/2-IN-1 also inhibits IL-4 and IL-13 with IC50s of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a)[1].

Applications: COVID-19-immunoregulation

Formula: C19H19BF3N5O3

References: [1]Alan Long, et al. Boron containing pyrimidine compounds, compositions comprising them, methods and uses thereof. WO2023244775A1.

CAS Number: 3023876-01-6

Molecular Weight: 433.19

Compound Purity: 98.36

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Interleukin Related;JAK

• SKU: MEXHY-162248-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162248-10
• Package Unit: 10 mg
• Quantity Unit: STK