JCP251, CAS 62252-26-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 7-amino-4-chloro-3-methoxy-1H-2-benzopyran-1-one

Purity: ≥95%

Formula Markup: C10H8ClNO3

Formula Weight: 225.62816

CAS Number: 62252-26-0

Notes: JCP251 is a protease inhibitor.{46644} It inhibits neutrophil elastase when used at a concentration of 5 µM and reduces the activity of HIV protease and caspase-3 by 70 and 68%, respectively, when used at a concentration of 100 µM in cell-free assays.{46644,46645} JCP251 decreases amyloid-β (1-40) (Aβ40; Item No. 21617) and Aβ42 (Item No. 20574) levels in HEK293 cells expressing wild-type and Swedish mutant amyloid precursor peptide (APP; IC50s = ~30 µM for both).{46646}

• SKU: CAY28712-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28712-5
• Package Unit: 5 mg
• Quantity Unit: STK