JD-5037, CAS 1392116-14-1

Product Description: JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM.

Applications: Cancer-programmed cell death

Formula: C27H27Cl2N5O3S

References: [1]Chorvat RJ. Peripherally restricted CB1 receptor blockers. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4751-60./[2]Knani I, et al. Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome. Mol Metab. 2016 Oct 22;5(12):1187-1199./[3]Mukhopadhyay B, et al. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology. 2015 May;61(5):1615-26.

CAS Number: 1392116-14-1

Molecular Weight: 572.51

Compound Purity: 99.38

Research Area: Metabolic Disease; Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Cannabinoid Receptor

• SKU: MEXHY-18697-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18697-100
• Package Unit: 100 mg
• Quantity Unit: STK