JNJ-1661010, CAS 681136-29-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide

Purity: ≥98%

Formula Markup: C19H19N5OS

Formula Weight: 365.5

CAS Number: 681136-29-8

Notes: Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier.{22625} At 20 mg/kg, JNJ-1661010 has been shown to elevate levels of AEA in rat brain.{22625} This compound has been used to examine the contribution of endocannabinoid signaling in experimental fibrosis.{22644}

• SKU: CAY14497-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14497-25
• Package Unit: 25 mg
• Quantity Unit: STK