Product Description: JNJ-303 is a specific delayed rectifier Kv blocker. JNJ 303 can potent block IKs with an IC50 value of 64 nM. JNJ-303 can be used for the research of diabetes, obesity and central nervous system[1][2].
Applications: COVID-19-immunoregulation
Formula: C21H29ClN2O4S
References: [1]Julie Albrecht, et al. The effect of the KV7/KCNE 1 inhibitor JNJ 303 on heart slices and the L-type calcium channel of cardiac cells./[2]Zhaohuan Huang, et al. Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism. Sci Adv. 2022 Jun 10;8(23):eabn5345.
CAS Number: 878489-28-2
Molecular Weight: 440.98
Compound Purity: 99.60
Research Area: Neurological Disease; Cardiovascular Disease