Product Description: JNJ-37822681 is a fast dissociating D2 antagonist with activity in inhibiting schizophrenia. JNJ-37822681 has high specificity for D2 receptors and is effective in animal models, inducing increased levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibiting antidepressant activity in the mouse tail suspension test, while having a good brain distribution and lower prolactin release.
Applications: Neuroscience-Neuromodulation
Formula: C17H17F5N4
References: [1]Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia
CAS Number: 935776-74-2
Molecular Weight: 372.34
Research Area: Others
Target: Dopamine Receptor