JNJ-42041935, CAS 1193383-09-3

Product Description: JNJ-42041935 is a potent, competitive and selective inhibitor of prolyl hydroxylase PHD; inhibits PHD1, PHD2, and PHD3 with pKi values of 7.91±0.04, 7.29 ±0.05, and 7.65±0.09, respectively.

Applications: COVID-19-immunoregulation

Formula: C12H6ClF3N4O3

References: [1]Barrett TD, et al. Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. Mol Pharmacol. 2011

CAS Number: 1193383-09-3

Molecular Weight: 346.65

Compound Purity: 99.79

Research Area: Inflammation/Immunology

Solubility: DMSO : ≥ 36 mg/mL

Target: HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-12832-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12832-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK