JNJ-42226314, CAS 1252765-13-1

Product Description: JNJ-42226314 is a competitive, highly selective and reversible non-covalent monoacylglycerol lipase (MAGL) inhibitor. JNJ-42226314 demonstrates dose-dependent enhancement of the major endocannabinoid 2-arachidonoylglycerol (2-AG) as well as efficacy in models of neuropathic and inflammatory pain[1].

Applications: Neuroscience-Neuromodulation

Formula: C26H24FN5O2S

References: [1]Wyatt RM, et al.Pharmacologic characterization of JNJ-42226314, [1-(4-fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a reversible, selective and potent monoacylglycerol lipase inhibitor.J Pharmacol Exp Ther. 2019 Dec 9.

CAS Number: 1252765-13-1

Molecular Weight: 489.56

Compound Purity: 99.47

Research Area: Neurological Disease

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: MAGL

• SKU: MEXHY-133130-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-133130-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK