JNJ-46778212, CAS 1363281-27-9

Product Description: JNJ-46778212 (VU 0409551) is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.

Applications: Neuroscience-Neurodegeneration

Formula: C20H17FN2O3

References: [1]Conde-Ceide S, et al. Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia. ACS Med Chem Lett. 2015 May 20;6(6):716-20.

CAS Number: 1363281-27-9

Molecular Weight: 352.36

Compound Purity: 99.37

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: mGluR

• SKU: MEXHY-19559-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19559-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK