JQEZ5, CAS 1913252-04-6

Product Description: JQEZ5 is a potent and selective EZH2 lysine methyltransferase inhibitor. JQEZ5 SAM-competitively inhibits polycomb repressive complex 2 (PRC2) with an IC50 of 80 nM. JQEZ5 has anti-tumor effects[1].

Applications: Cancer-programmed cell death

Formula: C30H38N8O2

References: [1]Zhang H, et al. Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer. Cancer Discov. 2016 Sep;6(9):1006-21.

CAS Number: 1913252-04-6

Molecular Weight: 542.68

Compound Purity: 98.08

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Histone Methyltransferase

• SKU: MEXHY-100846-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100846-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK