Product Description: JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models[1].
Formula: C23H28N4O3
References: [1]Hoon MA, et al., Compositions and methods for the inhibition of pruritus. WO2019090039.