K-756, CAS 130017-40-2

Product Description: K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC50s of 31 and 36 nM, respectively.

Applications: Cancer-programmed cell death

Formula: C24H27N5O3

References: [1]Okada-Iwasaki R, et al. The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase. Mol Cancer Ther. 2016 Jul;15(7):1525-34.

CAS Number: 130017-40-2

Molecular Weight: 433.50

Compound Purity: 99.25

Research Area: Cancer

Solubility: DMSO : 4.55 mg/mL (ultrasonic)

Target: PARP

• SKU: MEXHY-U00422-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-U00422-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK