K114, CAS 872201-12-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4,4'-[(2-bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis-phenol

Purity: ≥98%

Formula Markup: C22H17BrO2

Formula Weight: 393.27318

CAS Number: 872201-12-2

Notes: A fluorescent probe for the detection of amyloids; pH-dependent ex/em maxima = 370/450 nm, respectively, at pH 8.5; pH-dependent ex/em maxima = 420/520 nm, respectively, at pH 10.5; demonstrates increased fluorescence intensity in the presence of Aß40 fibrils; displays fiber-dependent excitation/emission maxima for silk moth (B. mori) silk, Chilean rose tarantula (G. rosea) web, and 5XFAD mouse brain amyloid fibers; has been used to detect amyloid plaques in postmortem hippocampus from patients with Alzheimer's disease.

• SKU: CAY34218-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34218-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Fluorescence